Natural history of a giant abdominal lipoma.

1 of 2 DESCRIPTION A 79-year-old woman was hospitalised for ischaemic stroke. She had 20 years history of a progressive abdominal enlargement. Ten years earlier abdominal CT had shown a giant abdominal lipoma. At that time she declined surgery. Physical examination revealed aphasia, right hemiparesis and massively enlarged abdominal volume ( fi gure 1 ). Ischaemic stroke was diagnosed and confi rmed by cranial CT. A new abdominal CT ( fi gure 2 ) with patient in left lateral decubitus revealed a huge hypodense retroperitoneal mass with soft tissue attenuation (A). Right kidney (B) was displaced to the left side of the abdomen and vena cava (C) was in front of the aorta (D). Biopsies from three different areas of the mass showed mature fat cells with no malignant cells. Surgery was refused by the patient and her relatives. The hypothesis of lipoma has been confi rmed by the long medical history and laboratory tests. Lipomas are benign tumours and the most common human mesenchymal neoplasia, with an estimated incidence of 10%. 1 They often present slow growth and small size. Nevertheless, they can achieve larger sizes. 2 To be considered a giant lipoma, the tumour has to be at least 10 cm in diameter or weigh above 1000 g. 3 Patients with small giant lipoma are usually asymptomatic. However, as the tumour grows, it may cause compression symptoms. The key teaching element of this case relates to the importance of surgically resecting asymptomatic lipomas. Although considered a benign tumour, the massive untreated lipoma has certainly jeopardised the patient quality of life.